CPUU fails with MAPI result: 0x80004005, Description: MAPI_E_CALL_FAILED

Hello,

I have an issue where the CPUU is failing for quite a few clients and wondered if anybody can shed some light on how this can be fixed.

Here is the error message the user is seeing shortly after the CPUU is launched:

"Either there is no default mail client or the current email client cannot fulfill the messaging request. Please run Microsoft Outlook and set it as the default mail client."

I checked the default email client and Outlook was set in Windows 10. I removed it, set it again but got the same error message when running the CPUU.

Below the last lines of the log:

1/7/2021 1:11:26 PM 44924  [Trace]       PDB file search path is set to 'C:\Users\Username\AppData\Local\OutlookUpdate'.
1/7/2021 1:11:26 PM 44924  [Info]        Cannot find PDB file at 'C:\Users\Username\AppData\Local\OutlookUpdate'.
1/7/2021 1:11:27 PM 44924  [Info]        Credentials in Windows Credential Manager:
1/7/2021 1:11:27 PM 44924  [Info]            'MS.Outlook.15:Username@monsterenergy.com:PUT' for user 'Username@monsterenergy.com'.
1/7/2021 1:11:27 PM 44924  [Info]            'OneDrive Cached Credential Business - Business1' for user 'd65a1746-faf8-4955-b831-3c2d740b8fac'.
1/7/2021 1:11:27 PM 44924  [Info]            'SSO_POP_Device' for user '02ksenonovuibapg'.
1/7/2021 1:11:27 PM 44924  [Info]            'Username@monsterenergy.com' for user 'Username@monsterenergy.com'.
1/7/2021 1:11:27 PM 44924  [Info]            'us-webaccess.monsterenergy.com' for user 'Username@monsterenergy.com'.
1/7/2021 1:11:27 PM 44924  [Info]            'virtualapp/didlogical' for user '02ksenonovuibapg'.
1/7/2021 1:11:27 PM 44924  [Info]    Default mail client: Microsoft Outlook.
1/7/2021 1:11:27 PM 44924  [Trace]       MSIComponentID: {6DB1921F-8B40-4406-A18B-E906DBEEF0C9}.
1/7/2021 1:11:27 PM 44924  [Trace]       MSIApplicationLCID: Microsoft\Office\16.0\Outlook.
1/7/2021 1:11:27 PM 44924  [Trace]       MSIOfficeLCID: Microsoft\Office\16.0\Common\LanguageResources.
1/7/2021 1:11:27 PM 44924  [Info]    Current directory is changed to 'C:\Program Files\Microsoft Office\root\VFS\ProgramFilesCommonX64\SYSTEM\MSMAPI\1033'.
1/7/2021 1:11:27 PM 70928  [Trace]       PDB file search path is set to 'C:\Users\Username\AppData\Local\OutlookUpdate'.
1/7/2021 1:11:27 PM 70928  [Info]        Cannot find PDB file at 'C:\Users\Username\AppData\Local\OutlookUpdate'.
1/7/2021 1:11:56 PM 44924  [Trace]       Locking mutex: _S-1-5-21-3354888888-901696995-1144947015-6376.
1/7/2021 1:11:57 PM 44924  [Trace]       Locking mutex: _outlook_mutex_.
MAPI result: 0x80004005, Description: MAPI_E_CALL_FAILED

Stack: 00000001402A5F92 00000001402A5C4B 00000001402A5227 00000001400399D5 000000014003B017 0000000140039C46 000000014025AF76 000000014025A9A8 00000001402516AE 0000000140043C6F 0000000140043556 000000014005470E 00000001402F7368 BaseThreadInitThunk RtlUserThreadStart
1/7/2021 1:11:57 PM 70928  [Info]    --- END LOG ---

Thank you and best regards,

Gerhard

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