Cross Domain Query (parent / child domain)

Hello Fellow Quest People.

I have a query in regarding to Virtualization... Again

We are considering virtualizing for instance Quest CMN or NME. This will be in a subdomain to where Exchange 2016 and Lotus Notes reside

Parent DOMAIN      Domain1.conteso.com   will host Exchange 2016 and DOMINO

Subdomain  domain2.conteso.com (sits as a child domain under domain1)  will host  Quest CMN or Quest NME

Can this work - assuming all accounts / ports are open / firewalls ?

I don't see this as an option in the 

Migrator for Notes to Exchange 4.16.1 - Pre-Migration Planning Guide

or the

Coexistence Manager for Notes 3.8.4 - User Guide